Catalogue Number: S8182-SEL
Manufacturer: | Selleck Chemicals |
Type: | Enzyme Inhibitors |
Shipping Condition: | Blue Ice |
Unit(s): | 10 mg, 200 mg, 50 mg |
Description: NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.