Rezolve








Our incredible reagent technology is plain to see
 

The visualisation of cellular structure and function, together with cellular metabolism and metabolites is vital for generating new knowledge for cell biology and to define mechanisms of disease. We develop reagents aimed at helping you to answer these important scientific questions.
Our reagents offer the ability to capture important cellular processes such as energy storage, cell signalling, metabolic processes and membrane dynamics in real time.
Use the reagents that supports you, to make more profound scientific breakthroughs.

 
WHAT THE LEADING REAGENT MUST HAVE Ensure
signal
separation
Limit
cellular
damage
Ease-of-use
High sensitivity (with small quantities of reagent)    
Large signal-to-noise ratio  
Long emission lifetimes / timegated visualisation    
Excitation in the visible (1-photon) or infrared (2-photons) region    
Resistance to photobleaching / fluorophore destruction    
Stability under physiological conditions      
Low molecular weight for reduced interference and enhanced uptake  
Minimal cytotoxicity allowing live cell imaging    


A proprietary platform that outperforms other reagents for clarity, simplicity and value


Our proprietary platform technology allows for the design of reagents capable of dissecting both structure and function at the sub-cellular level. These reagents offer enhanced sensitivity and spatial resolution, enabling high quality visualisation of sub-cellular function.
Our cell imaging reagents technology is based on small molecules chemistry. An interchangeable rare-earth core allows for optimization of absorption and emission profiles of the resulting reagents. The individually designed and coupled targeting motif then defines the reagents specificity.

Gain better insights to make more profound discoveries


When designing cell imaging reagents we deliver you tools with superior characteristics in the following areas:
  • Resistant to photobleaching
  • Low cytotoxicity
  • Compatible with live cell imaging
  • Easy to use, both in handling and in application

Imaging lipid biology


Lipids have important roles in energy storage, signalling, cell metabolism and are major structural components of all cellular membranes. Changes in lipid distribution and metabolism are a major factor in many metabolic diseases.
Our reagent Rezolve-L1 offers the ability of visualisation in high-resolution and real time the sub-cellular localisation of polar lipids.

Imaging carbohydrate distribution


Carbohydrates and cellular molecular machinery involved in carbohydrate production, interaction and transportation are essential to the simplest functionalities of life. Carbohydrates play a significant role in cellular energy metabolism, but also provide functions for cellular communication and recognition.
Over the next few months we will be launching reagents that utilize a sugar targeting motif for visualization in real time in live cells.