Founded in 2023, Ellis Bio is a biotechnology tools company driven by a vision to revolutionize genomic technologies and make cutting-edge epigenomic tools accessible to researchers and clinicians worldwide. Our journey began within the vibrant scientific community of The University of Chicago, where one of our flagship technologies—the SuperMethyl ™ Fast kit—was first developed by Scientific Founder Prof. Chuan He and Dr. Qing Dai. s


SuperMethyl™ Fast Bisulfite Conversion Kit

The SuperMethyl™ Fast Bisulfite Conversion Kit by Ellis Bio is a cutting-edge solution that redefines speed and efficiency in DNA methylation analysis. Engineered with an advanced, ready-to-use bisulfite conversion reagent, this kit simplifies the entire process — simply add the reagent to your sample and incubate for less than 10 minutes at 98°C.

Ultrafast Conversion
Achieve complete bisulfite conversion in less than 10 minutes — making it the fastest kit available for comprehensive DNA bisulfite conversion

High Efficiency
Consistently delivers over 99.5% conversion of unmethylated cytosines, ensuring accurate analysis while preserving methylated cytosines

Versatile Applications
Ideal for a variety of applications including PCR, methylation-specific PCR (MSP), arrays, library preps, and next-generation sequencing (NGS)

SuperMethyl™ Fast Beads
Catalog Number (SKU): SMF-50R-BEAD
Component Volume and Quantity:
SuperMethyl – Fast Conversion Buffer 1.5 mL x 7 vials
SuperMethyl – Fast Binding Buffer 28 mL
SuperMethyl – Fast Wash Buffer 14 mL
SuperMethyl – Fast Desulphonation Buffer 11mL
SuperMethyl – Fast Elution Buffer    1.8 mL
SuperMethyl – Fast Purification Beads 0.85 mL
SuperMethyl™ Fast Columns
Catalog Number (SKU): SMF-50R-COLUMN
Component Volume and Quantity:
SuperMethyl – Fast Conversion Buffer 1.5 mL x 7 vials
SuperMethyl – Fast Binding Buffer 28 mL
SuperMethyl – Fast Wash Buffer 7 mL
SuperMethyl – Fast Wash Buffer 7 mL
SuperMethyl – Fast Elution Buffer    1.5 mL
SuperMethyl – Spin Columns & Collection Tubes 50 pairs

SuperMethyl™ Max Bisulfite Conversion Kit (COMING SOON)

The SuperMethyl™ Max Bisulfite Conversion Kit by Ellis Bio is a cutting-edge solution that redefines what acceptable DNA damage is in DNA methylation analysis. Engineered with an advanced, ready-to-use bisulfite conversion reagent, this kit provides minimal DNA damage outperforming the current kits on the market. Looking to accelerate your research with better science?

Low Degradation
Optimised chemistry supports efficient bisulfite conversion while preserving DNA quality

Exceptional C-to-T Conversion Efficiency
Greater than 99.5% conversion rates

High Library Complexity
Produces libraries with greater complexity and larger insert sizes compared to conventional bisulfite conversion

Low-Input Compatible
Validated for 100 pg to 50 ng of cell-free DNA (cfDNA), genomic DNA (gDNA), or FFPE derived

NGS-Ready
Compatible with major library prep kits and sequencing platforms