The Proinsulin Total Chemiluminescence ELISA offers superior sensitivity compared to other kits in the market. The assay measures intact as well as Des (31,32) and Des (64,65) proinsulin. It utilizes a dual-monoclonal antibody sandwich format, tri-level control set, and 96-well microplate comprising removable strips
Broad Dynamic Range (5 – 3,000 pg/mL)
Significantly reduces sample preparation time by eliminating dilution steps and the guesswork involved in determining dilution factors, saving time and money. No guessing, no diluting, no repeating.
The assay offers a high sensitivity of 0.455 pg/mL.
100% cross reactivity to Human Intact Proinsulin, Human Des(64,65) Proinsulin, <0.6% cross reactivity to Human Insulin, and <0.1% 0% cross reactivity to Human C-Peptide
Lot Validation Package
Lot validation includes functional sensitivity, inter- and intra-assay precision, accuracy, LLOQ , and ULOQ
UBC Professor Bruce Verchere, PhD discusses the significance of proinsulin and insulin as biomarkers to probe beta cell dysfunction.
|Description:||Proinsulin (Total) Chemiluminescence ELISA|
|Sample Types:||Cell Culture, EDTA Plasma, Heparin Plasma, Serum, Tissue Culture|
|Sample Sizes:||50 µL|
|Available Sizes:||96 Tests, 96 Wells|
|Range:||5 pg/mL – 3000 pg/mL|
|Incubation:||2 hour(s) 30 minute(s)|
|Protocol:||Proinsulin (Total) Chemiluminescence ELISA|
|Material Safety Data Sheet:||Proinsulin (Total) Chemiluminescence ELISA|
|Regulatory Status:||Research Use Only. Not for Use in Diagnostic Procedures.|