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The nervous system, which refers to the combined central and peripheral nervous systems, is characterized by intricate interactions between neuronal and glial cells. Neurons receive, process, and relay both internal and external information. Glial cells, once thought to serve primarily as “nerve glue”, are now known to be necessary for neuronal cell support, metabolism, and activity. Identifying a particular glial or neuronal cell population is essential for dissecting its specific role in maintaining nervous system function. Each cell type expresses various factors, including adhesion molecules, cytoskeletal proteins, transcription factors, and surface receptors, among others. Detection of these factors, or “markers”, through the use of antibodies is the best way to distinguish individual cell types for further study.