GeneTex’s KO/KD-Validated QKI Antibodies for Neuroscience Research
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| QUAKING/QKI belongs to the STAR (Signal Transducer and Activator of RNA) family of RNA-binding proteins and functions in the differentiation of myelin-forming oligodendrocytes and Schwann cells. In the adult mouse CNS, QKI is highly expressed in glial cells such as astrocytes and oligodendrocytes. Active in multiple post-transcriptional gene regulation processes (i.e., mRNA stabilization, splicing, export, and translation), QKI plays pivotal roles in glial cell differentiation and maturation. Key targets of QKI include myelin basic protein (MBP), glial fibrillary acidic protein (GFAP), and myelin-associated glycoprotein (MAG). Moreover, QKI is a candidate gene for various pathologies, including myelin disorders, glioblastoma, and schizophrenia.
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| GeneTex’s neuroscience catalog lists an excellent selection of antibodies to detect QKI for many applications and species. | ||||||||||||||||||||||||||||||
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