Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes.
Granulocyte macrophage–colony stimulating factor (GM-CSF) is secreted in response to inflammatory stimuli such as LPS, IL-1, and TNF-α by a variety of different cells, including endothelium, fibroblasts, muscle cells, and macrophages, and by activated T cells. GM-CSF is glycosylated in its mature form.
GM-CSF recombinant protein is used primarily as a cell culture additive. The availability of Bovine, Canine, Chicken, Equine, Human, Mouse, Rabbit, and Swiine GM-CSF recombinant proteins will aid scientists in growing and maintinaing specific cells and cell types in vitro.
The GM-CSF recombinant proteins were produced in yeast without the use of tags. Recombinant proteins produced in yeast are naturally endotoxin free, properly folded, biologically active, and may be post-translationally modified. Many scientists find that these properties make proteins produced in yeast preferable over E. coli-produced proteins, especially for cell culture applications.
Kingfisher Biotech’s GM-CSF recombinant proteins are lyophilised, available in convenient sizes (5, 25, and 100 micrograms). Additional information, including product specifications can be found at https://www.stratech.co.uk/kingfisher-biotech-inc and in the GM-CSF product list.
Kingfisher Biotech is focused on providing kits and reagents to the animal health and animal model research community. Currently, the Kingfisher Biotech product portfolio contains over 1000 products. Kingfisher Biotech products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use.