Alithea Genomics, high throughput transcriptomics solutions for research and biomarker discovery.


Products

High throughput transcriptomics.
Made simple, with BRB-seq.

The BRB-seq library preparation protocol makes it possible for the first time to perform RNA-seq on a large number of RNA or blood samples in a fast, robust and cost-effective way.

Discover BRB-seq 

As opposed to standard RNA-seq – where all samples need to be processed individually throughout the library preparation workflow – with BRB-seq all samples can be pooled and processed in one single tube right after the first reverse transcription reaction.

Inside BRB-seq: the BRB-seq oligos

Each kit contains unique BRB-seq barcodes that are designed to “tag” in the a sample-specific manner all the mRNA molecules of a given sample.

Once all the samples have been barcoded, they can be immediately pooled together in one tube, which drastically reduces costs and manual operations of the downstream steps and, as a consequence, of the overall workflow.

Products and Services

MERCURIUS   BRB-seq kit (Cat. 0001-AGE)

 

96, 384 or up-to 1536 RNA samples in one-tube.

Try out our kits and experience in first person the convenience of BRB-seq.

 

With our kits, 96, 384 and up-to 1536 RNA samples can be pooled and processed in one tube, which drastically increases cost-efficiency and throughput.
As opposed to standard RNA-seq – where all samples need to be processed individually throughout the library preparation workflow – with BRB-seq all samples can be pooled and processed in one single tube right after the first reverse transcription reaction.

Our optimized BRB-seq barcodes facilitate robust and uniform NGS data distribution across large numbers of samples.

Each kit contains unique BRB-seq barcodes that are designed to “tag” in the a sample-specific manner all the mRNA molecules of a given sample.

Once all the samples have been barcoded, they can be immediately pooled together in one tube, which drastically reduces costs and manual operations of the downstream steps and, as a consequence, of the overall workflow.

MERCURIUS   Blood BRB-seq kit (Cat. 0002-AGE)

 

96, 384 or up-to 1536 RNA samples in one-tube.

The Blood BRB-seq kits are ideal for large-scale analysis of blood RNA samples.

With them, all the benefits of standard BRB-seq, such as throughput and cost-efficiency, are combined with an integrated globin depletion strategy.

As opposed to standard RNA-seq – where all samples need to be processed individually throughout the library preparation workflow – with BRB-seq all samples can be pooled and processed in one single tube right after the first reverse transcription reaction.

Our optimized BRB-seq barcodes facilitate robust and uniform NGS data distribution across large numbers of samples.

Each kit contains unique BRB-seq barcodes that are designed to “tag” in the a sample-specific manner all the mRNA molecules of a given sample.

In addition to the convenience of large-scale multiplexing, our integrated globin depletion strategy lead to efficient and specific depletion of globin genes.

Once all the samples have been barcoded, they can be immediately pooled together in one tube, which drastically reduces costs and manual operations of the downstream steps and, as a consequence, of the overall workflow.

MERCURIUS   BRB-seq service

From RNA extraction to data analysis.

Our service extends the cost and throughput benefits of BRB-seq to any user, also those that do not currently possess the required facilities or expertise.

Depending on the user’s needs, we will run the service directly or help implement BRB-seq at their service provider/core facility of choice.

As opposed to standard RNA-seq – where all samples need to be processed individually throughout the library preparation workflow – with BRB-seq all samples can be pooled and processed in one single tube right after the first reverse transcription reaction.

Our optimized BRB-seq barcodes facilitate robust and uniform NGS data distribution across large numbers of samples.

Each kit contains unique BRB-seq barcodes that are designed to “tag” in the a sample-specific manner all the mRNA molecules of a given sample.

Once all the samples have been barcoded, they can be immediately pooled together in one tube, which drastically reduces costs and manual operations of the downstream steps and, as a consequence, of the overall workflow.


How do BRB-seq pre-processing results look like?

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BRB-seq vs Truseq

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What is BRB-seq?

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A story of fruit flies, sleep and RNA-seq

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Whole blood RNA-seq to guide COVID-19 treatment

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Functional drug screening: microarray vs RNA-seq

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Blood transcriptomics: sequence deeper or sequence more samples?

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Single and bulk RNA-seq working together to boost immuno-oncology

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