Founded in 2023, Ellis Bio is a biotechnology tools company driven by a vision to revolutionize genomic technologies and make cutting-edge epigenomic tools accessible to researchers and clinicians worldwide. Our journey began within the vibrant scientific community of The University of Chicago, where one of our flagship technologies—the SuperMethyl ™ Fast kit—was first developed by Scientific Founder Prof. Chuan He and Dr. Qing Dai. s

The SuperMethyl™ Fast Bisulfite Conversion Kit by Ellis Bio is a cutting-edge solution that redefines speed and efficiency in DNA methylation analysis. Engineered with an advanced, ready-to-use bisulfite conversion reagent, this kit simplifies the entire process — simply add the reagent to your sample and incubate for less than 10 minutes at 98°C.

Ultrafast Conversion
Achieve complete bisulfite conversion in less than 10 minutes — making it the fastest kit available for comprehensive DNA bisulfite conversion
High Efficiency
Consistently delivers over 99.5% conversion of unmethylated cytosines, ensuring accurate analysis while preserving methylated cytosines
Versatile Applications
Ideal for a variety of applications including PCR, methylation-specific PCR (MSP), arrays, library preps, and next-generation sequencing (NGS)
| SuperMethyl™ Fast Beads |
| Catalog Number (SKU): SMF-50R-BEAD |
| Component Volume and Quantity: |
| SuperMethyl – Fast Conversion Buffer 1.5 mL x 7 vials |
| SuperMethyl – Fast Binding Buffer 28 mL |
| SuperMethyl – Fast Wash Buffer 14 mL |
| SuperMethyl – Fast Desulphonation Buffer 11mL |
| SuperMethyl – Fast Elution Buffer 1.8 mL |
| SuperMethyl – Fast Purification Beads 0.85 mL |
| SuperMethyl™ Fast Columns |
| Catalog Number (SKU): SMF-50R-COLUMN |
| Component Volume and Quantity: |
| SuperMethyl – Fast Conversion Buffer 1.5 mL x 7 vials |
| SuperMethyl – Fast Binding Buffer 28 mL |
| SuperMethyl – Fast Wash Buffer 7 mL |
| SuperMethyl – Fast Wash Buffer 7 mL |
| SuperMethyl – Fast Elution Buffer 1.5 mL |
| SuperMethyl – Spin Columns & Collection Tubes 50 pairs |
The SuperMethyl™ Max Bisulfite Conversion Kit by Ellis Bio is a cutting-edge solution that redefines what acceptable DNA damage is in DNA methylation analysis. Engineered with an advanced, ready-to-use bisulfite conversion reagent, this kit provides minimal DNA damage outperforming the current kits on the market. Looking to accelerate your research with better science?

Low Degradation
Optimised chemistry supports efficient bisulfite conversion while preserving DNA quality
Exceptional C-to-T Conversion Efficiency
Greater than 99.5% conversion rates
High Library Complexity
Produces libraries with greater complexity and larger insert sizes compared to conventional bisulfite conversion
Low-Input Compatible
Validated for 100 pg to 50 ng of cell-free DNA (cfDNA), genomic DNA (gDNA), or FFPE derived
NGS-Ready
Compatible with major library prep kits and sequencing platforms