Innovation with Impact

Powering the Companies in Pursuit of a Healthier Future

From animal vaccines to human nutrition, Proliant Health & Biologicals produces industry-leading proteins to serve companies in microbiological, life sciences, bio-pharmaceutical, and veterinary sciences across the globe.


Superior Purity for Reliable Performance

We manufacture our products with the exacting standards of our partners in mind.

Products

pure & dependable

Exceptional Reliability for Accurate Results

Diagnostic instruments are only as reliable as the materials used to make them. PHB controls its entire manufacturing process to create exceptionally pure protein products that ensure accurate and consistent results when it matters most.

BSA for Diagnostics

Maximum Purity and Performance

PHB’s manufacturing process minimizes the minor variances in BSA purity that can have major impacts on diagnostic accuracy and reliability.

Caprylate Stabilized BSA

Reliability for the Most Demanding Applications

Known for their reliability and consistency, PHB’s Standard Grade (caprylate stabilized) products tout industry-leading specifications, offering improved performance across the board. The entire range of Standard Garde (caprylate stabilized) products offer peace of mind when your most sensitive applications demand results.

Versatile BSA for Standards, Blocking, and More

Proliant’s Standard Grade (Caprylate Stabilized) pH 7.0 provides a BSA in its native state, providing the most stable form of BSA for the most sensitive cell culture, diagnostic, and research applications. Caprylate stabilized BSA has exceptional purity and low interference, utilizing heat-shock fractionation designed to inactivate proteases and other potentially interfering enzymes.

Superior Quality and Reliability

None Detected
IgG
Purity for a more consistent experience

None Detected
Protease
For a wide array of application usage

≤1 EU/mg
Endotoxin
To keep the opportunity for interference low

Applications

Protein, Conjugate or Enzyme Stabilizer
To help with structural conformation despite outside forces

Hybridization
To provide stability to sensitive environments

Protein standard or blocker
For immunoassays, flow cytometry, serology, and more

Specifications

Standard Grade (Caprylate Stabilized) pH 7.0
Protein (Dry Basis) ≥ 98.0%
Purity (Albumin) ≥ 98%
Solubility (4% Solution in Water) Clear-to-slightly hazy
Moisture ≤ 5.0%
pH (10% Solution in Water) 6.5 to 7.5
IgG None Detected
Protease None Detected
Endotoxin ≤ 1 EU/mg
Ash < 2%
Heavy Metals ≤ 10 ppm

Caprylate Stabilized BSA

Reliability for the Most Demanding Applications

Known for their reliability and consistency, PHB’s Standard Grade (caprylate stabilized) products tout industry-leading specifications, offering improved performance across the board. The entire range of Standard Garde (caprylate stabilized) products offer peace of mind when your most sensitive applications demand results.

Caprylate Stabilized Products

The Definitive Low-pH BSA

Unmatched Performance in Lower pH Applications with Unbeatable Antifouling Properties

Proliant Standard Grade (Caprylate Stabilized) pH 5.2 BSA is the established standard for lower pH applications because of its undetectable protease and IgG along with the fact that it is also free of contaminants that can cause background interference. At pH 5.2, our BSA has optimal anti-fouling properties, making it a superior blocking agent across a variety of applications.

Consistency for Low pH Applications

5.0 to 5.6
pH (10% Solution in Water)
Ideal for lower pH applications

None Detected
IgG
Allowing more consistent results

≥ 96%
Protein (Dry Basis)
Better consistency with higher purity

Applications

Protein, Conjugate or Enzyme Stabilizer
To assist in the retention of structural conformation

Protein standard or diluent
For immunoassay integrity, stability of components and more

Protease-Sensitive Assays
To include RIA, EIA, Fluorescent and Chemiluminescent

Specifications

Standard Grade (Caprylate Stabilized) pH 5.2
Protein (Dry Basis) ≥ 96.0%
Purity (Albumin) ≥ 96%
Solubility (4% Solution in Water) Clear-to-slightly hazy
Moisture ≤ 5.0%
pH (10% Solution in Water) 5.0 to 5.6
IgG None Detected
Ash < 3%

Cell Culture Powders

High-Performance, Growth Enhancing BSA

The Standard for Interference-Free Cell Culture and Microbial Applications

Cohn Analog BSA undergoes extensive membrane dialysis and filtration to minimize analytes. Taking those additional processing steps allows us to provide a high-performance, growth enhancing BSA that can be used for especially sensitive cell culture and microbial applications where no interference is non-negotiable.

High-Performing and Extraordinarily Pure

≥ 96%
Protein (Dry Basis)
Superior purity

6.5 to 7.5
pH
Encompassing a range of applications

None Detected
IgG
For better assay integrity

Applications

Growth of fastidious microorganisms
Including Leptospira and B. bergdorferi

Vaccine Production
For improved performance

Selected Cell Culture Applications
Preserving and extending reproductive cell viability

Specifications

CAPRYLATE STABILIZED COHN ANALOG
Protein (Dry Basis) ≥ 96.0%
Solubility (4% Solution in Water) Clear-to-slightly hazy
Moisture ≤ 5.0%
pH (10% Solution in Water) 6.5 to 7.5
IgG None Detected
Endotoxin < 10 EU/mg
Ash < 3%

Fatty-Acid Free BSA

Exceptional Performance and Consistency

The Ultimate Solution for Interference-Free Assays and Enzymatic Precision

Fatty-acid free BSA touts the lowest levels of total lipids, fatty acids, and non-esterified fatty acids of any albumin currently available commercially. It is optimal in applications where fatty acids can interfere with functionality such as hormone, cholesterol, or nucleic acid assays and is the preferred choice for protein fillers or bases so fatty acids won’t also be included. Fatty-acid free BSA is also highly recommended for enzymatic assays due to there being no EDTA.

Improved Stability, Reduced Interference

< 0.010%
Non-Esterified Fatty Acids (NEFA)
When enhanced sensitivity is required

None Detected
Protease
Highly purified for consistency

None Detected
IgG
When specificity matters

Applications

Protease-Sensitive Immunoassays
Including RIA, EIA, fluorescent, chemiluminescent

Superior Blocking
For immunohematology, nucleic-acid based and enzymatic assays

Protein Stabilization
For better functionality and preservation

Specifications

Fatty-Acid Free BSA
Protein (Dry Basis) ≥ 98.0%
Purity (Albumin) ≥ 98%
Solubility (4% Solution in Water) Clear-to-slightly hazy
Moisture ≤ 5.0%
pH (10% Solution in Water) 6.5 to 7.5
Non-Esterified Fatty Acids (NEFA) < 0.010%
IgG None Detected
Protease None Detected
Endotoxin ≤ 1 EU/mg
Ash < 2%
Heavy Metals ≤ 10 ppm

Enhanced Effectiveness

Specialized To Block Free Thiol Groups

Enhanced Albumin for Effective Assays

Sulfhydryl Blocked BSA offers some of the most effective BSA through a manufacturing process that effectively blocks free thiol groups to provide a high monomer albumin and ensures less crossreactivity.

It can be used in acridinium ester chemiluminescence, and because it contains fatty acid and does not have residual EDTA, sulfhydryl blocked BSA is a great blocker for enzymatic assays.

Reproducible Results Through Less Cross-Reactivity

≤ 0.1 mol/mol Albumin
Free Sulfhydryl Content
Higher monomer, less cross reactivity

None Detected
IgG
Low interference for sensitive applications

6.5 – 7.5
pH (7% Solution in Water)
Ultra compatible

Applications

Acridinium ester chemiluminescence
For the most sensitive applications

Enzymatic assays
For more reliable measurements

Thiol sensitive applications
Including quantification of thiol containing analytes

Specifications

Sulfhydryl Blocked
Protein (Dry Basis) ≥ 98.0%
Purity (Albumin) ≥ 98%
Solubility (4% Solution in Water) Clear-to-slightly hazy
Moisture ≤ 5.0%
pH (7% solution)/Temp 6.5-7.5/Ambient
Free Sulfhydryl Content ≤ 0.1 mol/mol albumin
IgG None Detected
Protease None Detected
Sodium ≤ 15.0 mg/g
Chloride ≤ 6.0 mg/g

BGG for Diagnostics

World-class Diagnostic BGG

Bovine Gamma Globulin for Enhanced Accuracy and Exceptional Results

BGG Powder

Exceptional Prevention of Non-Specific Binding

Unleashing the Power of Superior Blocking for Immunoassay Excellence

Proliant Bovine Gamma Globulin offers exceptional passive blocking capability and is great for complex applications due to its unique protein makeup and superior solubility. When BGG is paired with BSA, it offers even greater blocking power to help address heterophilic antibodies that may lead to false positives and reduced immunoassay performance by depleting the concentration of these interfering antibodies.

To achieve the best results, Bovine Gamma Globulin blocking conditions should be optimized for maximal signal-to-noise ratio and should be tested against appropriate controls.

Superior blocking power

≥ 96.0%
Purity
Purity for better blocking

< 10.0 mg/g
Sodium
For improved consistency

6.8 to 7.2
pH (7% Solution in Water)
To maximize application usability

Applications

Heterophilic antibody reduction
A passive blocker to maximize reduction

Immunoassay blocking
As the sole blocking agent or combined with other blockers

Immunoassay controls and calibrators
For improved consistency and reproducibility

Specifications

Bovine Gamma Globulin
Protein (Dry Basis) ≥96%
Moisture ≤ 5.0%
pH (7% solution)/Temp 6.8 to 7.2
Sodium 0 to 10.0 mg/g
Chloride 0 to 24.0 mg/g

Serums for Cell Culture

Superior Growth Factors and Reproducibility

With the largest lot sizes in the industry and unmatched consistency and technical support, PHB serums offer unfailing performance.

Serums

Unbeatable Consistency, Industry-Leading Lot Sizes

Traceable, Sterile, Consistent, and Globally Exportable

Our adult bovine serum undergoes meticulous collection, thawing, pooling, and sterile filtration processes to minimize bioburden and control endotoxin levels. Fully traceable, it meets global export standards. With industry-leading lot sizes, unbeatable consistency, and comprehensive technical support, Proliant sets a new standard in serum excellence.

Reproducible Results, Superior Growth Factors

≤10 EU/mL
Endotoxin
Low interference for sensitive applications

6.5 to 8.5
pH
For a wider variety of cell growth applications

20,000L
Single Lot Size
Save time and dollars

Applications

Cell Proliferation and Viability Assays
For assay-specific cell population analysis

Antibody Production Amplifier
Maximize high-quality antibody generation

Media Supplement
For vaccine production and further manufacturing

Specifications

Adult Bovine Serum
Total Protein As Reported
Endotoxin ≤ 10 EU/mL
pH 6.5 to 8.5
Osmolality 240-330 mOsm/kg
Haemoglobin ≤ 50 mg/dL
Virus Testing OMAR/9CFR
Asepsis None Detected
BVDV None Detected
Mycoplasma None Detected
Pathogen Inducing Cytopathy None Detected
Pathogen Inducing Haemadsorption None Detected

Serums

Industry-leading Performance and Reliability

Unmatched quality for superior outcomes

Derived from healthy calves aged 4-28 days, our NBCS undergoes meticulous collection, thawing, pooling, and sterile filtration processes. With focus on bioburden control and endotoxin management, it ensures superior quality. Fully traceable and meeting global export standards, Proliant sets a new benchmark in NBCS. We offer industry-leading lot sizes, unmatched consistency, and comprehensive technical support for your research endeavors.

High Quality, Better Performance

≤10 EU/mL
Endotoxin
For highly sensitive applications

6.5 to 8.5
pH
For use in a number of cell growth applications

240-330 mOsm/kg
Osmolality
To ensure the conditions for cell growth are ideal

Applications

Cell culture powerhouse
As an ideal media supplement

Fetal Bovine Serum (FBS) Extender
Expand the use of your fetal bovine serum

Cell Proliferation and Viability Assays
For the analysis of assay-specific cell populations

Specifications

Newborn Bovine Calf Serum
Total Protein > 45g/kg
Endotoxin ≤ 10 EU/mL
pH 6.5 to 8.5
Osmolality 240-330 mOsm/kg
Haemoglobin ≤ 25 mg/dL
Virus Testing OMAR/9CFR
Asepsis None Detected
BVDV None Detected
Mycoplasma None Detected
Pathogen Inducing Cytopathy None Detected
Pathogen Inducing Haemadsorption None Detected

Product Literature