SFC Co., Ltd., is a leading fine chemicals company established in 1998. In 2014, SFC Co., Ltd. launched a new brand of SFCprobes® using the proprietary assets of professor B. R. Cho’s group at Korea University.
SFCprobes® is dedicated to making a difference in the field of two-photon probe (TPP) and related imaging technologies based on more than one decade of accumulated knowledge and experience.
Backed by their deep understanding of biological phenomena as well as molecular design, SFCprobes® provides superb TPP’s, and imaging technologies developed and tailored for biological, medicinal and pharmaceutical applications.
SFCprobes® has a strong belief that TPP technology should be one of the key scientific tools to make human society healthier by significantly advancing biology and medicine.
|Catalogue code||Description||Target||Key Advantages|
|T0001-SFC||CL – Two-Photon Probe||Lipid rafts / Membrane||Greater sensitivity to solvent polarity and stronger TPEF emission than Laurdan.|
|T0002-SFC||CL2 – Two-Photon Probe||Lipid rafts / Membrane||Direct visualisation of lipid rafts in live cells & living tissue at 100-250um using TPM.|
|T0003-SFC||SL2 – Two-Photon Probe||Lipid rafts / Membrane||Preferentially locates in the plasma membrane. Effective at lower concentration in live cells for >1 hr with minimal internalisation.|
|T0004-SFC||Aca1-AM – Two-Photon Probe||Ca2+||Detects dynamic levels of intracellular free Ca2+ ions in living cells and tissues. No interference from other metal ions or membrane-bound probes.|
|T0005-SFC||AZn2 – Two-Photon Probe||Zn2+||Selectively detects intracellular free Zn2+ ions in live cells for >1000s.|
|T0006-SFC||ANa1 – Two-Photon Probe||Na+||Selectively detects Na+ in live cells & living tissues at 100-200um for >1 hr using TPM|
|T0007-SFC||SSH-Mito – Two-Photon Probe||H2S||Ratiometric TPP for mitochondrial thiols. Low cytotoxicity and pH insensitivity. Visualise at 90-190um in live tissues.|
|T0008-SFC||SSH-M2 – Two-Photon Probe||Thiol||Marked change in emission colour blue – yellow in response to H2S. Low cytotoxicity. Allows quantitative analysis of H2S levels.|
|T0009-SFC||AL1 – Two-Photon Probe||Lysosome||Easily loaded into cells & tissues. Can visualise transportation of acidic vesicles along the axon at 120um for >1100s in live tissue.|
|T0010-SFC||SG1 – Two-Photon Probe||Beta-galactosidase (β-gal)||Marked blue – yellow colour change in response to β-gal. Easy loading, insensitivity to pH and ROS, high photo-stability, low cytotoxicity.|
|T0011-SFC||SAD1 – Two-Photon Probe||Beta-amyloid||Readily enters the brain through the BBB and can directly 3D monitor indicudial Aβ plaque in living mouse brain at >380um. Minimum background emission and photo-bleaching artifacts.|
|T0012-SFC||AG2 – Two-Photon Probe||D-glucose||Easily taken up by cancer cells and tissues via glucose-specific translocation. pH independent at a wide range of physiological pH values. Negligible cytotoxicity, high photo-stability.|
|T0013-SFC||ANO1 – Two-Photon Probe||Nitric Oxide||Rapid and specific NO response, pH insensitivity. Easily loaded into cells. Allow real-time monitoring of NO in living tissues at 100-180um over long periods.|
|T0014-SFC||PN1 – Two-Photon Probe||Hydrogen Peroxide
|Marked blue – green colour change in response in H2O2, good ROS selectivity, low cytotoxicity and insensitivity to pH. Can visualise H2O2 in live cells at >90-180um.|