StemoniX provides products and services for drug discovery and development. We structure human iPSC-derived cells into physiologically relevant microtissues with accelerated cell maturity that mimic the native organ tissue. Predictive, accurate, and consistent, our in vitro human cell-based products enable scientists to quickly and economically conduct research with improved outcomes in a simplified workflow.


Product Categories

Consistent cultures of neurons and astrocytes co-matured from a single donor source

Structured human cardiomyocytes in 2.5D and 3D formats

microOrgan®  Technology

Complex human biology for complex questions

StemoniX’s microOrgan plates contain ready-to-use functional microtissues engineered from human induced pluripotent stem cells (iPSC). Designed to enable high-throughput human drug screening without the need for drugs to enter a human body, our microOrgans offer significant cost and time savings for our partners. 

microBrain® 3D Assay Ready

HUMAN IPSC-DERIVED CORTICAL SPHEROIDS PRE-PLATED FOR HIGH THROUGHPUT SCREENING AND DRUG DISCOVERY

microBrain® 2D Assay Ready

MATURE, BALANCED CULTURE OF HUMAN IPSC-DERIVED CORTICAL NEURONS AND ASTROCYTES PRE-PLATED IN HIGH DENSITY SCREENING PLATES

Neural Progenitor Cells

MULTIPOTENT HUMAN IPSC-DERIVED NPCS IN A CRYOPRESERVED FORMAT THAT CAN CONSISTENTLY GENERATE HIGH YIELDS OF FUNCTIONAL CORTICAL NEURONS AND ASTROCYTES

microHeart® Assay Ready

STRUCTURED HUMAN CARDIOMYOCYTES PRE-PLATED IN HIGH DENSITY SCREENING PLATES TO MATCH NATIVE HUMAN HEART TISSUE

microHeart® Cell Ready

NOVEL HIGH DENSITY SCREENING PLATES THAT ALIGN PLATED CARDIOMYOCYTES INTO PHYSIOLOGICALLY RELEVANT STRUCTURES FOR DRUG DISCOVERY AND DEVELOPMENT

Stemonix offer custom services, find out more information below.

Let’s Discover Together!

Our scientific team includes world experts in stem cell biology, drug discovery, materials engineering, and bio- and micro-manufacturing. Let our team help you with your disease modeling and assay development design and execution. Together, we can discover and develop more effective and safer medicines.

StemoniX Discovery as a Service (DaaS) program provides access to our physiologically relevant human induced pluripotent stem cell (iPSC)-based platforms along with scientific experts to design, perform, and analyze your experiments. From cells to assays to data, we leverage expertise in neural and cardiac cell-based toxicology and drug discovery and development studies to generate high quality, consistent results for your custom service needs including assay development and  drug screening (efficacy and toxicity)

StemoniX DaaS offers a full range of expertise and capabilities for in vitro functional and phenotypic high-throughput screening. StemoniX can screen our off-the-shelf microBrain and microHeart platforms or create a custom model to suit your needs. 

StemoniX scientist testing high-throughput plate

Webinars

StemoniX / Molecular Devices Webinar

Due to the structural and functional complexity of the Central Nervous System (CNS), the ability to obtain accurate and predictive in-vitro models for drug discovery and toxicology screening has been lacking. To fill this gap, StemoniX has developed the microBrain 3D platform: pre-plated neural spheroids composed of human iPSC-derived cortical neurons and astrocytes of uniform composition and size.

This presentation details how the Molecular Devices FLIPR Penta and ImageXpress Micro Confocal systems have been used to functionally and structurally characterize microBrain 3D spheroids from both healthy and disease sources.

Key highlights:

  • Use of microBrain neuronal microspheroids

  • Calcium oscillations in neural spheroids

  • 3D image analysis of compound treated neural spheroids

  • Multi-parametric evaluation of neurotoxicity effects

BIO2020 Digital Panel Discussion

StemoniX CEO, Ping Yeh, participated in a panel on

Organs on a Chip and AI: Realizing Potential Efficiencies in Drug Discovery.

This panel explored how highly scalable iPSC-based technologies could deliver significant cost and time savings to the pharmaceutical industry, reduce animal testing, and potentially lead to safer, more effective human clinical trials.


Neural Progenitor Cells

StemoniX Neural Progenitor Cells used in microBrain StemoniX human iPSC-Derived Neural Progenitor Cells (NPCs) are a homogeneous, self-renewing and multipotent Read More…

microHeart®

Winner of CONNECT’s Most Innovative Product Award for Life Science Diagnostics & Research Tools A Structured Environment for Cell Performance Read More…

microBrain® 2D Assay Ready

Structure Leads to Improved Cell-Based Assay Outcomes A Structured Environment for Cell Performance StemoniX® microBrain® 2D Assay Ready, pre-plated product is Read More…

microBrain® 3D Assay Ready

Structure Leads to Improved Cell-Based Assay Outcomes Neural Network Structure and Cell Maturity The neural network structure of microBrain cortical Read More…

microOrgan Platform Technology

Stemonix’s microOrgan plates contain ready-to-use functional microtissues engineered from human induced pluripotent stem cells (iPSC). Designed to enable high throughput Read More…