AIF1 (Allograft Inflammatory Factor 1, AIF-1, Ionized Calcium-binding Adapter Molecule 1, Protein G1, G1, IBA1) (MaxLight 650)
Catalogue Number: 029413-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | AIF-1|allograft inflammatory factor 1|IBA1|interferon gamma responsive transcript|ionized calcium-binding adapter molecule 1|IRT1|IRT-1|protein G1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 13A155 (20A12.1) |
| Isotype: | IgG1, kappa |
| Immunogen: | Synthetic linear peptide corresponding to human AIF1. |
| Application: | WB, IHC |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. The allograft inflammatory factor-1 (AIF-1) is a 17kD interferon-gamma inducible Ca(2+)-binding EF-hand protein that is encoded within the HLA class III genomic region. AIF-1 is known to be identical with ionized Ca(2+)-binding adaptor 1, microglia response factor-1, and daintain. AIF-1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and the activation and function of macrophages. It is also shown to be expressed in macrophages and microglial cells in autominnume disesases such as experimental autoimmune encephalomyelitis, and neuritis and uveitis models.
Additional Text
Accession Number
NP_001614
Uniprot ID
P55008
Gene Name
AIF1
Specificity
Recognizes human AIF1. Species Crossreactivity: Mouse and rat.
Purification
Protein G purified
Gene ID
199
Antibody Clonality
Monoclonal
029413-ML650 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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