CDH5 (Cadherin-5, 7B4 Antigen, Vascular Endothelial Cadherin, VE-cadherin, CD144) (MaxLight 490)

Catalogue Number: 029442-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	7B4\|7B4 antigen\|cadherin 5, type 2 (vascular endothelium)\|cadherin 5, type 2, VE-cadherin (vascular epithelium)\|cadherin-5\|CD144\|cd144 antigen\|endothelial-specific cadherin\|vascular endothelial cadherin\|VE-cadherin
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	BV6
Isotype:	IgG2a, kappa
Immunogen:	HUVEC cells
Application:	FC, ICC, WB, IHC

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Human Vascular Endothelial (VE)-cadherin is a calcium-dependent adhesion molecule strictly located at cell-to-cell junctions. VE-cadherin is present in all types of endothelium (veins, arteries, capillary and large vessels). Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. Cadherins may thus contribute to the sorting of heterogeneous cell types. VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. VE-cadherin also associates with alpha-catenin forming a link to the cytoskeleton.

Additional Text

Gene Name

CDH5

Uniprot ID

P33151

Gene ID

1003

Accession Number

NP_001786

Specificity

Recognizes human VE-cadherin.

Purification

Protein G purified

Antibody Clonality

Monoclonal

029442-ML490 Datasheet

Price

£1,064.00

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Quantity
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