JAM-A (Junctional Adhesion Molecule A, Junctional Adhesion Molecule 1, JAM-1, CD321, F11r, Jam1, Jcam, Jcam1) (MaxLight 490)
Catalogue Number: 029519-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | 13A203 (BV11) |
| Isotype: | IgG2b, kappa |
| Immunogen: | H5V murine heart capillary endothelial cells. |
| Application: | FC, ICC, IP |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Functional adhesion molecule A is found in endothelial and epithelial tight junctions and is involved in the inflammatory enlistment of mononuclear cells containing LFA-1. JAM-A is linked to atherogenesis, platelet activation, transmigration of leukocytes and angiogenesis. JAM-A is also found to be important in the development of many different organ systems, and is mostly expressed in the epithelial parts and the embryonic vasculature. JAM-A is indicated to play a role in epithelial permeability, inflammation and proliferation in the intestine, aiding in homeostasis.
Additional Text
Accession Number
NP_766235
Specificity
Recognizes mouse JAM-A.
Purification
Protein G purified
Antibody Clonality
Monoclonal
029519-ML490 Datasheet
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations