ADA, CT (ADA1, Adenosine deaminase, Adenosine aminohydrolase) (APC)

Catalogue Number: 030746-APC-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Type:Monoclonal Primary Antibody - Conjugated
Alias:adenosine aminohydrolase|adenosine deaminase
Shipping Condition:Blue Ice
Unit(s): 200 ul
Host name: Mouse
Clone: 608CT2.1.3
Isotype: IgG1
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 287-314 in the C-terminal region of human ADA.
Application: WB, FLISA

Description

Description: This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

Additional Text

Caution

FOR RESEARCH USE ONLY

Uniprot ID

P00813

Accession Number

NP_000013.2

Gene ID

100

Gene Name

ADA

Specificity

Human

Purification

Protein G purified

Antibody Clonality

Monoclonal