ARSA, CT (ARSA, Arylsulfatase A, Cerebroside-sulfatase, Arylsulfatase A component B, Arylsulfatase A component C) (APC)

Catalogue Number: 030787-APC-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Type:Monoclonal Primary Antibody - Conjugated
Alias:arylsulfatase A|ASA|cerebroside-sulfatase|epididymis secretory sperm binding protein|MLD
Shipping Condition:Blue Ice
Unit(s): 200 ul
Host name: Mouse
Clone: 498CT24.1.2
Isotype: IgG2a
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 408-439 in the C-terminal region of human ARSA, UniProt Accession #NP_000478.2; P15289.
Application: WB, FLISA

Description

Description: ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this protein lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene ID

410

Gene Name

ARSA

Uniprot ID

P15289

Accession Number

NP_000478.2

Specificity

Recognizes human ARSA.

Purification

Protein G purified

Antibody Clonality

Monoclonal