CD4 (T-cell surface glycoprotein CD4,CD4,) (Azide free) (HRP)

Catalogue Number: 030850-HRP-USB

Manufacturer:United States Biological
Preservative:Azide-free
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD4 antigen (p55)|CD4 receptor|CD4mut|T-cell surface antigen T4/Leu-3|T-cell surface glycoprotein CD4
Shipping Condition:Blue Ice
Unit(s): 200 ul
Host name: Mouse
Clone: OKT4
Isotype: IgG2b, kappa
Immunogen: Recombinant protein corresponding to CD4
Application: ELISA, WB

Description

Description: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

CD4

Gene ID

920

Uniprot ID

P01730

Accession Number

NP_000607.1

Specificity

Recognizes human CD4.

Purification

Protein G purified

Antibody Clonality

Monoclonal