CD334 (Fibroblast Growth Factor Receptor 4, FGFR4, TKF, JTK2, FGFR-4)
Catalogue Number: 052034-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 4FR6D3 |
| Isotype: | IgG1, kappa |
| Immunogen: | NIH 3T3 cells transfected with full length human CD334 |
| Application: | FC, ICC |
Description
Description: CD334/FGFR4 (fibroblast growth factor receptor 4), a transmembrane tyrosine kinase, which is expressed in many tissues, such as in lung, kidney, muscle, heart, pancreas, intestine and other, acts as a receptor for several fibroblast growth factors, namely FGF1, FGF2, FGF6, FGF8, and FGF19. Interaction with these growth factors initiates in cell the signaling cascades leading to the mitogenesis and cell differentiation. Presence of CD334 Gly338Arg allele correlates with prognostic parameters in various cancer studies. CD334 plays multiple roles in the organism, including those of muscle regeneration, cholesterol-to-bile acid metabolism, or glucose homeostasis.
Additional Text
Gene Name
FGFR4
Gene ID
2264
Uniprot ID
P22455
Purification
Protein A purified
Antibody Clonality
Monoclonal
SUPPORT
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PRODUCT
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DELIVERY
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