CRTAC1 (Cartilage Acidic Protein 1)
Catalogue Number: 052053-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 24H1 |
| Isotype: | IgG2b |
| Immunogen: | Recombinant protein corresponding to Ser28-Cys661 from human CRTAC1, expressed in NS0 cells |
| Application: | ICC |
Description
Description: CRTAC1 (cartilage acidic protein 1; also CEP-68) is a 95-105kD member of a novel family of EGF domain-containing proteins. It is secreted by articular chondrocytes and may play a role in either cartilage matrix organization or cell-matrix adhesion. Mature human CRTAC1 is 634 amino acids (aa) in length. It contains four FG-GAP (PheGly-GlyAlaPro) domains (aa 46-437) and one EGF-like motif (aa 559-605). Multiple splice forms exist. There are two alternate start sites at Met9 and Met211 that may be accompanied by a 39 aa substitution for the C-terminal 55 aa, or an 84 aa substitution for aa 545-661. Over aa 28-661, human CRTAC1 shares 91% aa identity with mouse CRTAC1. This form in mouse, however, is more equivalent to the human isoform that shows a C-terminal 39 aa substitution. In this case, there is 95% aa identity between mouse and human.
Additional Text
Gene Name
CRTAC1
Gene ID
55118
Uniprot ID
Q9NQ79
Purification
Protein A purified
Antibody Clonality
Monoclonal
SUPPORT
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PRODUCT
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DELIVERY
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