CD303

Catalogue Number: 052057-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 15E3
Isotype: IgG1, kappa
Immunogen: CD303 ectodomain fused with human IgG Fc domain
Application: ELISA, FC, ICC, IHC

Description

Description: CD303 is an ~38kD type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.

Additional Text

Gene ID

170482

Gene Name

CLEC4C

Uniprot ID

Q8WTT0

Purification

Protein A purified

Antibody Clonality

Monoclonal