HDAC6 (Histone Deacetylase 6)

Catalogue Number: 052201-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 236
Isotype: IgG2b, kappa
Immunogen: Human HDAC6
Application: FC, ICC, WB

Description

Description: Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.

Additional Text

Gene Name

HDAC6

Gene ID

10013

Purification

Protein A purified

Antibody Clonality

Monoclonal

UniProt ID

Q9NSW6