Adiponectin (ACRP30, apM-1, ADIPOQ)
Catalogue Number: 052309-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | D05-9C7 |
| Isotype: | IgG1 |
| Immunogen: | Recombinant protein corresponding to Glu19-Asn244 from human Acrp30, expressed in E. coli. |
| Application: | ELISA |
Description
Description: Adiponectin is a fat-derived hormone which suppresses glucose production in the liver and enhances fatty acid oxidation in skeletal muscle, and acts as a messenger to allow communication between adipose tissue and other organs (Wang and Scherer, 2016). Adiponectin can elicit several downstream signaling events, including the insulin signaling pathway. Anti-diabetic, anti-inflammatory, and anti-atherogenic effects of adiponectin have been identified, and the protein sensitizes cells to insulin. Decreased adiponecin levels may play a role in development of type 2 diabetes, and therefore, adiponectin has been suggested as a potential therapeutic target for diabetes (Achari and Jain 2017).
Additional Text
Gene Name
ADIPOQ
Gene ID
9370
Uniprot ID
Q15848
Antibody Clonality
Monoclonal
Purification
Purified by Protein G chromatography from tissue culture supernatant.
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