PER2
Catalogue Number: 052321-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 7H4.1 |
| Isotype: | IgG1, kappa |
| Immunogen: | GST-tagged recombinant protein corresponding to human PER2. |
| Application: | WB, IHC |
Description
Description: Period circadian protein homolog 2 (PER2), or Circadian clock protein PERIOD2, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. It is a negative element in the circadian transcriptional loop by Influencing clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. PER2 negatively regulates CLOCK NPAS2-BMAL1 BMAL2-induced transactivation. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior.
Additional Text
Gene ID
8864
Gene Name
PER2
Uniprot ID
O15055
Accession Number
NP_073728
Purification
Protein G purified
Antibody Clonality
Monoclonal
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