Monoclonal Antibody to p105/p50 (Clone: ABM20H5)
Catalogue Number: 10-6021-ABO
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | NFKB1 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Mouse |
| Clone: | ABM20H5 |
| Isotype: | IgG1, kappa |
| Immunogen: | A partial length recombinant p50 protein (amino acids 1-200) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: p50 (KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B) family of transcription factors plays important roles in various biological processes including apoptosis, stress response, immunity, and inflammation. Activation of p50 regulates the expression of inflammatory genes crucially involved in the pathogenesis of inflammatory diseases. It governs the expression of adhesion molecules that play a pivotal role in leukocyte-endothelium interactions. p50 activation plays an essential role in the activation of mesangial cells and macrophages through the transcriptional induction of inflammatory mediators of glomerular inflammation and injury.
Additional Text
Gene Name
NFKB1
Gene ID
4790
Purification
Protein G purified
Uniprot ID
P19838
Antibody Clonality
Monoclonal
Application Notes
Western blot analysis: 1-2 µg/ml
10-6021 Datasheet
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