Monoclonal Antibody to Mouse PD-1 (Clone: ABM5F42)
Catalogue Number: 10-7612-ABO
10-7612 Image
10-7612 Image
Fig:1- Cell surface flow analysis of mPD-1 in Con A treated Mouse Splenocytes using 0.5 µg/10^6 cells of mPD-1 antibody (Clone: ABM5F42). Green represents isotype control; red represents anti-mPD-1 antibody. Goat anti-rat PE conjugate was used as secondary antibody.
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Programmed cell death protein 1, Protein PD-1, CD279 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rat |
| Clone: | ABM5F42 |
| Isotype: | IgG2b, kappa |
| Immunogen: | partial length recombinant protein (a.a 07-211) of mPD-1 was used as the immunogen for this antibody. |
| Application: | FACS |
Description
Description: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Additional Text
Gene Name
PDCD1
Purification
Protein G purified
Uniprot ID
Q02242
Gene ID
18566
Antibody Clonality
Monoclonal
Application Notes
FACS: 0.5-1 µg/10^6
10-7612 Datasheet
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