iFluor® 700 Anti-human CD1 Antibody *OKT-6*

Catalogue Number: 100110J0-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: OKT-6
Isotype: IgG1
Immunogen:
Application: FC, IF

Description

Description: OKT-6 is an anti-human monoclonal antibody that recognizes the CD1a antigen. CD1a (alternatively called T6 or R4) is a 49 kD member of the Ig superfamily that is found on the surface of cells like T cells, B cells, dendritic cells and macrophages. CD1 has been thought to be involved with key biological processes such as immune response, particularly adaptive immune response. Additionally, in some organisms, it acts to positively regulate T cell mediated cytotoxicity. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as β-2-Microglobulin and CD74. CD1 is a moderately popular antibody target, with over 15000 publications in the last decade. CD1a is vital to innate immunity and immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 700 (ex/em = 690/713 nm).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months