iFluor® 560 Anti-human CD2 Antibody *RPA-2.10*
Catalogue Number: 100210A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | RPA-2.10 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: RPA-2.10 is an anti-human monoclonal antibody that is specific for the CD2 antigen. CD2 (sometimes referred to as T11, Rosette receptor, Erythrocyte receptor or LFA-2) is a 45 kD single-pass type I membrane protein that is located on the surface of cells such as T cells, B cells and NK cells. In certain organisms, CD2 positively regulates interleukin-8 secretion, enhances myeloid dendritic cell activation and is an enhancer of interferon-gamma secretion. Also, it has been thought to be involved with important biological processes like cell-cell adhesion, specifically heterotypic cell-cell adhesion. CD2 is involved with key cellular pathways, in particular, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like CD48, LFA-3 and CD58. CD2 is a moderately popular antibody target, with over 16000 publications in the last decade. CD2 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of costimulatory molecules and immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 577/35 nm bandpass filter (for example, as in the Luminex Amnis ImageStream).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
100210A1 Protocol
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