Anti-Human ApoE4 (5B5) Mouse IgG MoAb 10025
Catalogue Number: 10025-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 200 ug, 10 ug |
| Host name: | Mouse |
| Clone: | 5B5 |
| Isotype: | IgG, IgG1 |
| Immunogen: | Synthetic peptide of a part of Human ApoE4 |
| Application: | WB, IHC |
Description
Description: Apolipoprotein E (ApoE) is a structural component of very low-density lipoprotein (VLDL) synthesized by the liver and intestinally synthesized chylomicrons. It is also a constituent of a subclass of high-density lipoproteins (HDLs) involved in cholesterol transport activity among cells. One of the most important roles of ApoE is to mediate high affinity binding of chylomicrons and VLDL particles that contain ApoE to the low-density lipoprotein (LDL) receptor. This allows for the specific uptake of these particles by the liver that is necessary for transport preventing the accumulation in plasma of cholesterol rich remnants. There are indications that ApoE is also involved in immune system regulation, nerve regeneration and muscle.
Additional Text
Purification
Affinity Purified
Antibody Clonality
Monoclonal
10025 Datasheet
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