PerCP/Cy5.5 Anti-human CD3 Antibody *SK7*
Catalogue Number: 100331U1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | SK7 |
| Isotype: | |
| Immunogen: |
Description
Description: The SK7 monoclonal antibody reacts with human CD3e, a 20 kD member of the Ig superfamily often found on the surface of t cells, tregs and nkt cells. In many organisms, CD3 positively regulates interleukin-2 biosynthetic process, enhances cell-matrix adhesion and is a positive regulator of gene expression. Moreover, it plays a role in essential cellular pathways, for example, the T cell receptor signaling pathway, negative regulation of smoothened signaling pathway and apoptotic signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like TCR. CD3 is a very popular antibody target, with over 80000 publications in the last decade. CD3e is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to PerCP/Cy5.5 (ex/em = 489/679 nm). It is compatible with the 488 nm laser and 702/85 nm bandpass filter (for example, as in the Luminex Amnis FlowSight).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
100331U1 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations