XFD700 Anti-human CD4 Antibody *RPA-T4*
Catalogue Number: 100411A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | RPA-T4 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: RPA-T4 is an anti-human monoclonal antibody that targets the CD4 antigen. CD4 (sometimes called T4 or Leu3a) is a 55 kD transmembrane glycoprotein that is expressed on the surface of cells such as granulocytes, T cells and macrophages. CD4 acts in vital cellular pathways, for instance, the T cell receptor signaling pathway, interleukin-15-mediated signaling pathway and enzyme linked receptor protein signaling pathway. Furthermore, in many organisms, it promotes interleukin-2 biosynthetic process, upregulates peptidyl-tyrosine phosphorylation and acts to positively regulate I-kappaB kinase/NF-kappaB signaling. CD4 has been associated with key biological processes such as membrane organization, specifically fusion of virus membrane with host plasma membrane, and is associated with a variety of biologically interesting macromolecules/ligands, namely, gp120 and Lck. CD4 is a very popular antibody target, with over 180000 publications in the last decade. CD4 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to XFD700 (ex/em = 696/719 nm). XFD700 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 700 (Alexa Fluor® is the trademark of ThermoFisher).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
100411A1 MSDS
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