XFD750 Anti-human CD8 Antibody *OKT-8*
Catalogue Number: 100821B1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | OKT-8 |
| Isotype: | IgG2a |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: OKT-8 is an anti-human monoclonal antibody that forms an immune complex with the CD8a antigen. CD8a (alternatively called T8 or MAL) is a 32 - 34 kD transmembrane glycoprotein that is located on the surface of cells such as T cells. CD8 is a component of essential cellular pathways, namely, the transmembrane receptor protein tyrosine kinase signaling pathway and cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like Lck and MHCI. CD8 is a very popular antibody target, with over 120000 publications in the last decade. CD8a has a variety of applications in immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD750 (ex/em = 752/776 nm). XFD750 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 750 (Alexa Fluor® is the trademark of ThermoFisher).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
100821B1 MSDS
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