iFluor® 560 Anti-human CD11a Antibody *R7-1*
Catalogue Number: 101140A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | R7-1 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: R7-1 is an anti-human monoclonal antibody that forms an immune complex with the CD11a antigen. CD11a (alternatively called αL Integrin or Integrin alpha-L) is a 170 - 180 kD transmembrane glycoprotein that is found on the surface of cells like T cells, NK cells, macrophages, granulocytes and B cells. CD11a has been closely linked to critical biological processes like cell-cell adhesion, particularly leukocyte cell-cell adhesion. In addition, it is involved with key cellular pathways, in particular, the integrin-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1, 2, 3 and 4 and CD18. CD11a is a fairly uncommon antibody target, with a little more than 3700 publications in the last decade. Even still, CD11a is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of cell adhesion and immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 585/16 nm bandpass filter (for example, as in the Thermo Fisher Attune NxT).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
101140A1 Protocol
SUPPORT
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PRODUCT
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DELIVERY
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