iFluor® 560 Anti-human CD11a Antibody *TS-1/22.1.1.13*
Catalogue Number: 101150A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | TS-1/22.1.1.13 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: TS-1/22.1.1.13 is an anti-human monoclonal antibody that targets the CD11a antigen. CD11a (also known as ITGAL or LFA-1α chain) is a 170 - 180 kD transmembrane glycoprotein that is found on the surface of cells such as NK cells, T cells, macrophages and B cells. CD11a plays a role in vital cellular pathways, namely, the integrin-mediated signaling pathway. Also, it has been closely linked to key biological processes like cell-cell adhesion, especially leukocyte cell-cell adhesion. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like ICAM-1 and CD18. CD11a is a fairly uncommon antibody target, with a little more than 3000 publications in the last decade. Even still, CD11a is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of costimulatory molecules, neuroinflammation and innate immunity. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 582/15 nm bandpass filter (for example, as in the BD FACSAria™ III).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
101150A1 Protocol
SUPPORT
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PRODUCT
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DELIVERY
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