iFluor® 820 Anti-human CD14 Antibody *HI221*
Catalogue Number: 101400P0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | HI221 |
| Isotype: | IgM |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: HI221 is an anti-human monoclonal antibody that is specific for the CD14 antigen. CD14 (sometimes referred to as myeloid cell-specific leucine-rich glycoprotein or LPS receptor) is a glycoprotein that is found on the surface of cells like granulocytes and macrophages. CD14 plays a role in vital cellular pathways, namely, the apoptotic signaling pathway, lipopolysaccharide-mediated signaling pathway and cell surface receptor signaling pathway. In addition, in many organisms, it enhances interleukin-8 secretion, acts to positively regulate interferon-gamma production and positively regulates NIK/NF-kappaB signaling. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as Endotoxin and TLR4. CD14 is a very popular antibody target, with over 42000 publications in the last decade. CD14 has a variety of applications in neuroinflammation, neuroscience and cell biology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 820 (ex/em = 822/850 nm).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
101400P0 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations