iFluor® 560 Anti-human CD14 Antibody *61D3*
Catalogue Number: 101410A0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | 61D3 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: 61D3 is an anti-human monoclonal antibody that targets the CD14 antigen. CD14 (sometimes referred to as myeloid cell-specific leucine-rich glycoprotein or LPS receptor) is a transmembrane protein that is located on the surface of cells such as macrophages. CD14 acts in critical cellular pathways, for example, the toll-like receptor signaling pathway, cell surface receptor signaling pathway and lipopolysaccharide-mediated signaling pathway. Moreover, in certain organisms, it promotes interleukin-8 secretion, is a positive regulator of tumor necrosis factor production and is a promoter of type I interferon production. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like LY96. CD14 is a very popular antibody target, with over 42000 publications in the last decade. CD14 is essential for immunology, cell biology and neuroscience research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 586/14 nm bandpass filter (for example, as in the BD LSRFortessa™ X-20).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
101410A0 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations