Catalogue Number: 101601B1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | HI16a |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description: The HI16a monoclonal antibody recognizes human CD16a, a 50 - 65 kD transmembrane glycoprotein often located on the surface of neutrophils, natural killer cells and macrophages. CD16 is involved with critical cellular pathways, for instance, the Fc-gamma receptor signaling pathway involved in phagocytosis. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like IgG Fc. CD16 is a very popular antibody target, with over 25000 publications in the last decade. CD16a is essential for innate immunity research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD750 (ex/em = 752/776 nm). XFD750 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 750 (Alexa Fluor® is the trademark of ThermoFisher).
Monoclonal
See Protocol|12 months