XFD750 Anti-human CD16 Antibody *HI16a*

Catalogue Number: 101601B1-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 tests
Host name: Mouse
Clone: HI16a
Isotype: IgG1
Immunogen:
Application: FC, IF

Description

Description: The HI16a monoclonal antibody recognizes human CD16a, a 50 - 65 kD transmembrane glycoprotein often located on the surface of neutrophils, natural killer cells and macrophages. CD16 is involved with critical cellular pathways, for instance, the Fc-gamma receptor signaling pathway involved in phagocytosis. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like IgG Fc. CD16 is a very popular antibody target, with over 25000 publications in the last decade. CD16a is essential for innate immunity research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD750 (ex/em = 752/776 nm). XFD750 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 750 (Alexa Fluor® is the trademark of ThermoFisher).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months