iFluor® 800 Anti-human CD18 Antibody *HI18a*
Catalogue Number: 101800N1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | HI18a |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: HI18a is an anti-human monoclonal antibody that targets the CD18 antigen. CD18 (sometimes called Integrin beta-2, ITGB2 or beta 2) is a transmembrane glycoprotein that is found on the surface of cells like granulocytes, platelets, macrophages, dendritic cells and B cells. In many organisms, CD18 is an enhancer of neuron death, suppresses dopamine metabolic process and is a promoter of nitric oxide biosynthetic process. Additionally, it is involved with critical cellular pathways, for example, the integrin-mediated signaling pathway, cytokine-mediated signaling pathway and toll-like receptor 4 signaling pathway. CD18 has been associated with critical biological processes such as cell migration, particularly endothelial cell migration, and is associated with a variety of biologically interesting macromolecules/ligands, for example, CD11a, b and c. CD18 is a fairly uncommon antibody target, with a little more than 8300 publications in the last decade. Even still, CD18 is essential for signal transduction research, typically serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 800 (ex/em = 801/820 nm).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
101800N1 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations