iFluor® 560 Anti-human CD19 Antibody *HI19a*
Catalogue Number: 101900A0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | HI19a |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: HI19a is an anti-human monoclonal antibody that targets the CD19 antigen. CD19 (also known as T-cell surface antigen Leu-12 or B-lymphocyte surface antigen B4) is a 95 kD transmembrane glycoprotein that is found on the surface of cells like B cells and stem cells. CD19 plays a role in critical cellular pathways, in particular, the antigen receptor-mediated signaling pathway and B cell receptor signaling pathway. Furthermore, in certain organisms, it plays a role in the upregulation of phosphatidylinositol 3-kinase activity, positively regulates release of sequestered calcium ion into cytosol and plays a role in the upregulation of protein kinase B signaling. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands such as CD81 and Leu-13. CD19 is a very popular antibody target, with over 36000 publications in the last decade. CD19 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 582/15 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
101900A0 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations