XFD750 Anti-human CD19 Antibody *SJ25C1*

Catalogue Number: 101911B0-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: SJ25C1
Isotype:
Immunogen:
Application: FC, IF

Description

Description: SJ25C1 is an anti-human monoclonal antibody that forms an immune complex with the CD19 antigen. CD19 (sometimes called T-cell surface antigen Leu-12 or B-lymphocyte surface antigen B4) is a 95 kD transmembrane glycoprotein that is located on the surface of cells such as stem cells, B cells and dendritic cells. CD19 is a member of key cellular pathways, in particular, the antigen receptor-mediated signaling pathway and B cell receptor signaling pathway. Additionally, in many organisms, it upregulates release of sequestered calcium ion into cytosol, promotes protein kinase B signaling and is a promoter of phosphatidylinositol 3-kinase activity. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as CD225. CD19 is a very popular antibody target, with over 36000 publications in the last decade. CD19 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography and conjugated to XFD750 (ex/em = 752/776 nm). XFD750 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 750 (Alexa Fluor® is the trademark of ThermoFisher).

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months