iFluor® 430 Anti-mouse CD19 Antibody *1D3*
Catalogue Number: 10194031-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Rat |
| Clone: | 1D3 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: 1D3 is an anti-mouse monoclonal antibody that is specific for the CD19 antigen. CD19 (sometimes referred to as B4) is a 95 kD transmembrane glycoprotein that is expressed on the surface of cells like B cells and stem cells. CD19 plays a role in essential cellular pathways, namely, the antigen receptor-mediated signaling pathway and B cell receptor signaling pathway. In addition, in some organisms, it is an enhancer of release of sequestered calcium ion into cytosol, is a promoter of protein kinase B signaling and is a positive regulator of phosphatidylinositol 3-kinase activity. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like CD225, CD81, PI3-kinase and fyn. CD19 is a very popular antibody target, with over 36000 publications in the last decade. CD19 has been widely used in costimulatory molecules and immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 430 (ex/em = 433/498 nm). It is compatible with the 445 nm laser and 510/80 nm bandpass filter (for example, as in the BD FACSAria™ III).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
10194031 Protocol
SUPPORT
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PRODUCT
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