Anti-Human MDMX (77A1) Mouse IgG MoAb 10201
Catalogue Number: 10201-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 10 ug |
| Host name: | Mouse |
| Clone: | 77A1 |
| Isotype: | IgG, IgG1 |
| Immunogen: | Human MDMX Recombinant protein |
| Application: | WB |
Description
Description: The p53 tumor suppressor protein is stabilized in response to cellular stress, resulting in activation of genes responsible for either cell cycle arrest or apoptosis. The cellular pathway for releasing normal cells from p53- dependent cell cycle arrest involves the MDM2 protein. Recently, a p53- binding protein with homology to MDM2 was identified and called MDMX. Like MDM2, MDMX is able to bind p53 and inhibit p53 transactivation. It is proposed that the MDMX protein may function to maintain a nuclear pool of p53 protein in undamaged cells.
Additional Text
Purification
Protein A purified
Antibody Clonality
Monoclonal
10201 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations