Catalogue Number: 102101B0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | HI21a |
| Isotype: | IgG2a |
| Immunogen: | |
| Application: | FC, IF |
Description: The HI21a monoclonal antibody recognizes human CD21, a 145 kD transmembrane glycoprotein frequently expressed on the surface of thymocytes and dendritic cells. CD21 plays a role in vital cellular pathways, namely, the complement activation, classical pathway. In addition, it has been associated with vital biological processes like immune response, specifically innate immune response. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as CD19, CD23 and C3d. CD21 is a fairly uncommon antibody target, with a little more than 5000 publications in the last decade. Even still, CD21 is essential for complement, innate immunity and immunology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD750 (ex/em = 752/776 nm). XFD750 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 750 (Alexa Fluor® is the trademark of ThermoFisher).
Monoclonal
See Protocol|12 months