Anti-Human Napsin A (TMU-Ad02) Mouse IgG MoAb

Catalogue Number: 10221-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Physical state:Lyophilized product from in PBS containing 1 % BSA and 0.05 % NaN3
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 50 ug, 5 ug
Host name:
Clone: TMU-Ad02
Isotype: IgG1
Immunogen: Synthetic peptide of the N-terminal part of human Napsin A


Description: A new protein isolated by two-dimensional immuno-electrophoresis from tissue of lung adenocarcinoma was identified as Napsin A, a new aspartic Proteinase. The reactivity of the antibody showed immunohistochemically in type II pneumocytes, alveolar macrophages, renal tubules and exocrine glands and ducts in pancreas. In particular, type II pneumocytes and alveolar macrophages showed strong staining. The specificity of the antibody is very interesting, which in primary lung adenocarcinoma, 47 out of 58 (81.0%) primary lesions were positive. All well-differentiated adenocarcinoma except those of goblet type showed strong staining. The antibody may be a useful tool as a tumor marker for primary lung adenocarcinoma.

Additional Text


Immunohistochemical study in histopathological types of lung carcinoma


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