iFluor® 560 Anti-human CD23 Antibody *EBVCS-5*
Catalogue Number: 102300A0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | EBVCS-5 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: EBVCS-5 is an anti-human antibody that forms an immune complex with the CD23 antigen. CD23 (sometimes referred to as FcεRII, BLAST-2 or B6) is a glycoprotein that is expressed on the surface of cells like platelets, granulocytes, T cells, dendritic cells and epithelial cells. CD23 is a component of important cellular pathways, for example, the cytokine-mediated signaling pathway and Notch signaling pathway. Furthermore, in certain organisms, it is a promoter of nitric-oxide synthase activity, acts to positively regulate killing of cells of other organism and positively regulates nitric-oxide synthase biosynthetic process. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like CD11b, CD21, IgE and CD11c. CD23 is a fairly uncommon antibody target, with a little more than 5800 publications in the last decade. Even still, CD23 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of . This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 586/15 nm bandpass filter (for example, as in the Miltenyi Biotec MACSQuant VYB).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
102300A0 Protocol
SUPPORT
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PRODUCT
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