iFluor® 560 Anti-human CD25 Antibody *7G7B6*
Catalogue Number: 102510A0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | 7G7B6 |
| Isotype: | IgG2a |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The 7G7B6 monoclonal antibody recognizes human CD25, a 55 kD glycoprotein often located on the surface of oligodendrocytes, T cells, B cells and thymocytes. In certain organisms, CD25 negatively regulates defense response to virus, downregulates inflammatory response and positively regulates activated T cell proliferation. Additionally, it is involved with critical cellular pathways, for instance, the interleukin-2-mediated signaling pathway, cell surface receptor signaling pathway and cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like IL-2. CD25 is a very popular antibody target, with over 40000 publications in the last decade. CD25 is vital to immunology research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 582/15 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
102510A0 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations