Anti-Human Endothelin-B Receptor (8Z11) Mouse IgG MoAb
Catalogue Number: 10253-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 10 ug |
| Host name: | Mouse |
| Clone: | 8Z11 |
| Isotype: | IgG, IgG2a |
| Immunogen: | Recombinant Human Endothelin-B Receptor (insect sf-9 cells) |
| Application: | WB, IHC |
Description
Description: Two kinds of receptors for Endothelin have been found, namely Endothelin-A (ET-A) receptor and Endothelin-B (ET-B) receptor. ET-A receptor is ET-1 specific and expressed in lung, aorta, atrium, liver, muscle, cerebral cortex, cerebellum, kidney, adrenal, duodenum, colon and placenta at the mRNA or cDNA level, while ET-B receptor lacks isopeptide specificity and is found in liver, lung, placenta, kidney, heart and brain. Cellular localization of ET-receptors in these organs or tissues, however, has not been elucidated, although stromal cells, but not epithelial cells of the breast, express ET-1 receptor in vitro.
Additional Text
Purification
Protein A purified
Antibody Clonality
Monoclonal
10253 Datasheet
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