Anti-Human MBD3 (3A3) Mouse IgG MoAb

Catalogue Number: 10281-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 10 ug
Host name: Mouse
Clone: 3A3
Isotype: IgG, IgG1
Immunogen: Synthetic peptide of part of C terminal of human MBD3 (EELARDGEAPLDKAC)
Application: WB


Description: Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG binding domain (MBD) can bind to single methylated CpGs and most of them are involved in transcription control. So far, five vertebrate MBD proteins have been described as MBD family members: BD1, MBD2, MBD3, MBD4 and MECP2.


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