XFD555 Anti-human CD29 Antibody *HI29a*
Catalogue Number: 10290161-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | HI29a |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The HI29a monoclonal antibody binds with human CD29, a 130 kD transmembrane protein often found on the surface of fibroblasts and platelets. CD29 is a member of essential cellular pathways, namely, the cytokine-mediated signaling pathway, integrin-mediated signaling pathway and CD40 signaling pathway. Also, it has been thought to be involved with vital biological processes like cell adhesion, especially cell adhesion mediated by integrin. In some organisms, CD29 acts to positively regulate apoptotic process, acts to positively regulate signaling receptor activity and enhances angiogenesis. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as VCAM-1. CD29 is a fairly uncommon antibody target, with a little more than 7000 publications in the last decade. Even still, CD29 has been widely used in cell adhesion, cell biology and stem cells research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to XFD555 (ex/em = 553/568 nm). XFD555 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 555 (Alexa Fluor® is the trademark of ThermoFisher). It is compatible with the 561 nm laser and 582/15 nm bandpass filter (for example, as in the BD FACSAria™ III).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
10290161 MSDS
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