Catalogue Number: 103000A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | MEM-268 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | FC, IF |
Description: MEM-268 is an anti-human monoclonal antibody that recognizes the CD30 antigen. CD30 (also known as Ber-H2, TNFRSF8 or Ki-1) is a 64 kD transmembrane protein that is located on the surface of cells like T cells and macrophages. In many organisms, CD30 promotes apoptotic process, is a suppressor of cell population proliferation and is an enhancer of TRAIL biosynthetic process. Additionally, it is a component of important cellular pathways, for instance, the tumor necrosis factor-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as CD153. CD30 is a fairly uncommon antibody target, with a little more than 6900 publications in the last decade. Even still, CD30 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of stem cells and immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 577/15 nm bandpass filter (for example, as in the Bio-Rad ZE5 Cell Analyzer).
Monoclonal
See Protocol|12 months